AKT-4 Tablets kit Side Effects and Dosage

Manufacturer of  AKT-4 Tablets kit

AKT-4 kit is manufactured by Lupin Laboratories Ltd ,India. Lupin Limited  was founded in 1968 by Dr. Desh Bandhu Gupta . Lupin Limited is the 2nd largest Indian pharma company by market capitalization .And it is the  14th largest generic pharmaceutical company globally . On the basis of International standards, these facilities are approved by international regulatory agencies including the US FDA, UK MHRA, Japan’s MHLW, TGA Australia, WHO, and the MCC South Africa.




Contents of AKT-4 Tablets kit 
AKT-4 kit is an anti-tuberculosis drug containing:  Rifampicin (1 cap) 450 mg, Pyrazinamide (2 tabs) 750 mg, Ethambutol (1 tab) 800 mg, Isoniazid 300 mg.

Usage of AKT-4 Tablets kit

AKT-4 Tablets kit used specifically for  the treatment of tuberculosis.

Side Effects of AKT-4 Tablets

Common side effects are drug induced gastritis presenting with nausea, vomiting

 .
The individual drug side effects are:


1) Isoniazide: hepatocellular jaundice, peripheral neuropathy  in bilateral foot,skin rashes.
2) Rifampicin: Jaundice, Flu like syndrome, rashes, decreased platelet count, orange coloured urine.
3) Ethambutol: retrobulbar optic neurits i.e vision problem.
4) Pyrazinamide: jaundice, hyperuricemia so can precipitate gout.

Pyridoxine (vit B6) 10 mg supplementation is required along with INH(isoniazid) for reducing side effects.You should be aware that rifampicin may change your urine colour to orange and is nothing to worry about.Visual functions should be tested before starting therapy or immediately thereafter LFTs (liver function tests) and uric acid levels should be monitored periodically  every 8 weeks or so. Medicines must be taken regularly. 


There will be no long lasting side effects. Once treatment is over (lasting from 6 months to 9 months ), the patient will be absolutely fine and normal in every respect.If your felling stomach upset take PAN -D 40 mg tablet half an hour before food.These side effects are temporary and after treatment will become alright.

Dosage and Administration of AKT-4 Tablets


The rifampicin capsule should be taken empty stomach and the rest of the tablets together after breakfast every day.
Follow all directions given to you by your doctor or pharmacist.

FDA pregnancy of AKT-4 Tablets
 AKT-4 Tablets falls under Category C of US FDA. Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well controlled studies in humans but potential benefits may warrant use of the drug in pregnant women despite potential risks

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