Gentamicin -Uses ,dosage , side effects

GENTAMICIN is an antibiotic under the class of Aminoglycoside and it is an important drug for the treatment of many serious gram-negative bacillary infections and usually is the aminoglycoside of first choice because of its low cost and reliable activity against all but the most resistant gram-negative aerobes. Gentamicin is given parenterally, ophthalmically,and topically.
Availability of Gentamicin
 Eye drops 0.3% w/v, cream 15g (0.1%w/w); INJECTION 2 ml ampoule (40 mg/ml),2 and 10 ml vials (40 mg/ml).

Amikacin-Uses and Side effects

AMIKACIN is an antibiotic under the class of aminoglycosides with amino sugars in glycosidic linkages. Amikacin is a semisynthetic product and used to treat conditions such as Bacterial infections, uncomplicated urinary tract infections, severe gram-negative infections resistant to gentamicin and tobramycin, and short term treatment of serious infections caused by Pseudomonas species, Escherichia coli, species of indole-positive and indole negative, Proteus, Klebsiella, Enterobacter, Serratia, Salmonella, Shigella and Acinetobacter. Get to know how Amikacin works, its side effects, precautions, interactions, and contraindications.

How does Amikacin work?

Amikacin has the capacity to kill the bacteria by binding to 30S ribosomes and inhibit bacterial protein synthesis. The drug penetrates the bacterial cell membrane through pores.

Amikacin has concentration-dependent bactericidal activity against Gram-negative aerobic bacteria, anaerobic bacteria are universally resistant because aminoglycoside transport into cells is oxygen-dependent.

NIPAH VIRUS INFECTION

NIPAH VIRUS INFECTION 

According to the World Health Organisation ,Nipah virus or NiV infection is a newly emerging zoonosis that cause severe disease in both animals and human beings .The natural host of the virus are fruit bats of the Pteropodidae Family ,Pteropus genus.
Niv first identified in 1998 during an outbreak in Malaysia.There is no vaccine for either humans or animals.The primary treatment for human cases is intensive medical care.

Zidovudine-uses, dosage and adverse effects

Zidovudine (ZDV)

Brands-Retrovir,Zidovir

Zidovudine (ZDV), also known as azidothymidine (AZT), is an antiretroviral medication used to prevent and treat HIV/AIDS.ZDV is of the nucleoside analog reverse-transcriptase inhibitor (NRTI) class.It works by inhibiting the enzyme reverse transcriptase that HIV uses to make DNA and therefore decreases replication of the virus.

Antiretroviral drugs do not cure HIV (human immunodeficiency virus) infection; they only temporarily suppress viral replication and improve symptoms. Patients receiving these drugs

require careful monitoring by appropriately trained health professionals in an adequately resourced setting. Rigorous promotion of measures to prevent new infections remains

essential and its need is not diminished by the availability of antiretroviral drugs. Effective therapy requires the simultaneous use of 3 or 4 drugs; alternative regimens are necessary

to meet specific requirements at start-up, to substitute for first-line regimens in cases of intolerance, or to replace failing regimens. The use of a 3- or 4-drug combination as specified in the WHO treatment guidelines is recommended. The use of fixed-dose preparations for these combinations is also recommended if the pharmaceutical quality is assured and interchangeability with the single products is demonstrated as specified by the relevant drug regulatory authority.

Pharmacovigilance Programme of India(PVPI)

Pharmacovigilance has been defined by the World Health Organization (WHO) as the science and activities relating to the detention ,assessment ,understanding and prevention of adverse effects or any other medicine related issues.
WHO established its programme for international drug monitoring in response to the Thalidomide tragedy happened in the year of 1961.Latter WHO decided to start pharmacovigilance programme at the country level .

Pharmacovigilance programme in India
The central drugs standard control organisation (CDSCO) New Delhi,under aegis of Ministry of Health and Family Welfare ,Government of India initiated a national wide pharmacovigilance programme in July 2010 with AIIMS New Delhi as National coordination Centre (NCC)for monitoring ADRs in the country for safe -guarding public health by ensuring the safety of medical products.The NCC was shifted from AIIMS ,New Delhi to Indian Pharmacopoeia Commision (IPC) Ghaziabad on 15th April 2011.

Amlopres 10 mg-Content, uses and Adverse effects

Manufacturer of Amlopres 10 mg tablet

Amlopres tablet is manufactured by Cipla Limited .

Content of Amlopres 10 mg tablet

Amlopres tablet contains Amlodipine .It is a calcium channel blocker and works by increasing the size of  arteries.

Amlopres 5 mg- Content, Indications and Adverse effects

Manufacturer of Amlopres 5 mg tablet

Amlopres tablet is manufactured by Cipla Limited .

Content of Amlopres 5 mg tablet

Amlopres tablet contains Amlodipine .It is a calcium channel blocker and works by increasing the size of  arteries.

Amlopres 2.5 mg; Content, Indications and Adverse effects

Manufacturer of Amlopres 2.5 mg tablet

Amlopres tablet is manufactured by Cipla Limited .

Content of Amlopres 2.5 mg tablet

Amlopres tablet contains Amlodipine .It is a calcium channel blocker and works by increasing the size of  arteries.

Aten 100 mg-Content ,Indications and Adverse effects

Manufacturer of  Aten 100 mg

Aten 100 mg tablet is manufactured by  Zydus Cadila Healthcare Ltd.

Aten 50 mg:Content ,Indications and Adverse effects

Manufacturer of  Aten 50 mg

Aten 50 mg tablet is manufactured by  Zydus Cadila Healthcare Ltd.

Aten 25 mg-content,uses and adverse effects

Manufacturer of  Aten 25 mg

Aten 25 mg tablet is manufactured by  Zydus Cadila Healthcare Ltd.

Atenolol-Availability,indications,adverse effects

Atenolol 

Atenolol  is a selective beta 1 receptor antagonist and belonging to the class of beta blockers.Beta blockers are primarily used for the treatment of cardiovascular diseases.

Lanoxin tablet Dosage

Manufacturer of Lanoxin tablet 0.25 mg

Lanoxin tablet is manufactured by GlaxoSmithKline Pharmaceutical Ltd.

Content of Lanoxin tablet 0.25 mg

Lanoxin tablet contains digoxin ,it is a cardiac glycoside .And also known as cardiotonic,increases the strength of cardiac muscle contractions and increases cardiac output.In mild heart failure ,digoxin inhibits the sympathetic nervous system and produces arterial vasodilation.It produces symptomatic improvement,increases exercise tolerance and reduces hospitalization, but it does not reduce mortality.

Digox tablet -Content, Usage ,side effects and dosage

Manufacturer of Digox tablet 0.25 mg

Digox tablet is manufactured by Cadila PVT LTD.

Content of Digox tablet 0.25 mg

Digox tablet contains Digoxin .Digoxin is a cardiac glycoside.And also known as cardiotonic,increases the strength of cardiac muscle contractions and increases cardiac output.In mild heart failure ,digoxin inhibits the sympathetic nervous system and produces arterial vasodilation.It produces symptomatic improvement,increases exercise tolerance and reduces hospitalization,but it does not reduce mortality.

Tachyra 100--content,uses ,side effects & Dosage

Manufacturer of Tachyra tablet 100 mg 

Tachyra tablet is manufactured by Cipla LTD. 

Content of Tachyra tablet 100 mg

Tachyra tablet contains Amiodarone hydrochloride .Amiodarone hydrochloride is a class 3 antiarrhythmic drug. Arrhythmia is a condition in which the heart beats an irregular or abnormal rhythm.

Tachyra tablet 200 mg-Side Effects & Dosage

Manufacturer of TACHYRA TABLET 200 mg 

Tachyra tablet is manufactured by Cipla LTD . 

Cordarone injection 50mg/ml-content,usage and adverse reactions

Manufacturer of INJECTION CORDARONE 50 mg/ml

Cordarone injection is manufactured by Sanofi Aventis . 

Cordarone tablet 200 mg-content,usage and adverse reactions

Manufacturer of CORDARONE TABLET 200 mg 

Cordarone tablet is manufactured by Sanofi Aventis . 

Cordarone tablet 100 mg-content,usage and adverse reactions

Manufacturer of CORDARONE TABLET 100 mg 

Cordarone tablet is manufactured by Sanofi Aventis .

Albendazole-drug class,uses,adverse drug reactions

Manufacturer of Albendazole:

Albendazole is manufactured by GlaxoSmithKline Pharmaceuticals Ltd, one of the world's leading research based pharmaceutical and healthcare companies.It is one of the oldest pharmaceuticals companies in India.Its prescription medicines range across therapeutic areas such as anti-infectives, dermatology, gynaecology, diabetes,cardiovascular,cancer and respiratory diseases. It also offers a range of vaccines, for the prevention of hepatitis A, hepatitis B, invasive disease caused by H, influenzae, chickenpox, dpt, rotavirus, cervical cancer and others.

Drug class of Albendazole:

Albendazole is an antihelminthic drug.Anthelmintics are an agent's that expel parasitic worms and other internal parasites from the body by either inhibiting the growth or killing them and without causing damage to the host tissue. 

Dapsone - Content,class ,usage,side effect and pregnancy category

Content of Dapsone tablet

Dapsone is diaminodiphenyl sulfone (DDS)