Manufacturer of INJECTION CORDARONE 50 mg/ml
Cordarone injection is
manufactured by Sanofi Aventis . 
Content of Cordarone injection
Cordarone injection contains Amiodarone hydrochloride .Amiodarone hydrochloride is a class 3
antiarrhythmic drug.Arrhythmia is a condition in which the heart beats an
irregular or abnormal rhythm.
Uses of Cordarone injection
- Ventricular arrhythmias
- Pulseless ventricular fibrillations(It is an
irregular rhythm caused by rapid,uncoordinated fluttering contractions of
the heart's lower chambers)
- Ventricular tachycardia(It is a fast heart's beat and a
pulse of more than 100 beats per minute)
- Atrial flutter and fibrillations
- All types of paroxysmal tachycardia(Paroxysmal atrial
tachycardia is a type of arrhythmia or irregular heartbeat)
Contraindications of Cordarone injection
Hypersensitive to
amiodarone or iodine.
Severe sinus node
dysfunction .
2 & 3 degree heart
block .
Cardiogenic shock.
Avoid bolus injection in congestive heart failure or cardiomyopathy.
Pregnancy.
Precautions of Cordarone injection
Liver-function and
thyroid -functions tests required before treatment and then every 6
months:hypokalemia(measure serum -potassium concentration before treatment
:severe bradycardia and conduction disturbance in excessive dosage :blood
pressure monitored closely .
Adverse effects of Cordarone injection
- Nausea
- Vomiting
- taste disturbance
- Raised serum transaminases (liver enzymes )
- Jaundice
- Bradycardia(abnormally slow heart action)
- Pulmonary toxicity(pneumonitis and fibrosis)
- Tremor
- Sleep disorders
- Hypothyroidism or hyper
- Reversible corneal microdeposits
- Phototoxicity
- Peripheral neuropathy or myopathy (usually reversible
on withdrawal)
- Hypersensitivity reactions
- Chronic liver diseases
- Haemolytic or aplastic anaemia
- Optic neuritis
- Anaphylaxis on rapid injection or hypotension
If any of the event
occured please contact your concerned doctor .
Pregnancy category -D
There is positive
evidence of human fetal risk based on adverse reaction data from
investigational or marketing experience or studies in humans,but potential
benefits may warrant use of the drug
in pregnant women despite
potential risks.
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